United States: Recent studies have shown that certain supplements can help older adults who are genetically predisposed to Alzheimer’s disease by allowing their brain cells to break slower.
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A recent study, whose results are published in JAMA Network Open, showed the benefits of fish oil supplements, which could significantly lower the pace of brain nerve cell deterioration in individuals carrying the APOE4 gene, a known risk factor for Alzheimer’s.
The Oregon Health & Science University (OHSU) conducted the research, which observed a major decrement in the loss of brain cell integrity within a year of treatment, as dailygalaxy.com reported.
Moreover, the findings also underlined the potential for personalized nutritional interventions based on genetic predisposition.
The authors also emphasized the need for larger clinical trials to confirm these results and establish definitive guidelines.
More about the study’s finding
As the scientists noticed, among patients with the APOE4 gene, those who received fish oil supplements experienced a slower rate of neuronal degradation than those who took a placebo.
This fact revealed the importance of focusing certain at-risk group with personalized interventions to maximize health benefits and, therefore, potentially slow down the initiations of neurodegenerative diseases, as dailygalaxy.com reported.
Benefits of Omega-3 fatty acids
According to experts, Omega-3 fatty acids, especially EPA and DHA, present in fish oil supplements, are famous for producing their anti-inflammatory properties.
The compounds also lower inflammation in blood vessel walls, lowering the risk of heart disease and cognitive decline.
Earlier studies also associated higher omega-3 intake with slower cognitive deterioration. Dr. Lynne Shinto, co-author of the study and professor of neurology at OHSU, said, “Our findings showed that over three years, there was not a statistically significant difference between placebo and the group that took fish oil. I don’t think it would be harmful, but I wouldn’t say you need to take fish oil to prevent dementia.”